PRO Biostructures is a part of the Laboratory of Protein Structure at International Institute of Molecular and Cell Biology in Warsaw, one of Poland’s leading research institutions.
Laboratory of Protein Structure started its activities in 2008. It is headed by Dr. Marcin Nowotny a crystallographer with significant scientific output – his structural wotrk has been published in Cell, Molecular Cell, EMBO Journal, Nature Structural Molecular Biology, Nature Communications). Dr. Nowotny received prestigious research grants, such as the ERC Starting Grant, the Wellcome Trust International Senior Research Fellowship (twice) and the Howard Hughes International Early Career Scientist Award.
LPS constantly develops scientifically, currently 17 qualified employees work in the laboratory, which is outfitted with state-of-the-art equipment. Funds from grants enable the lab to do cutting-edge research. LPS focuses on structural and biochemical studies of proteins, especially nucleic acid enzymes, using protein crystallography as a primary method. Proper functioning of these proteins in the body prevents mutations that can lead to the development of cancer.
LPS has closely cooperated with various pharmaceutical companies as a commercial services provider or partner in grants application.
More information on the research can be found at http://www.iimcb.gov.pl/
International Institute of Molecular and Cell Biology (IIMCB) in Warsaw commenced its scientific activity in 1999. As one of the few institutes in Poland it was established under an international agreement between the Polish government and UNESCO. Principles of operation are based on ideas of the best research institutions in the world. The Scientific Council is the International Advisory Committee, whose majority of members are scientists from abroad. The Committee elects heads of research groups on the basis of international competitions. Every few years, leaders of laboratories are evaluated (including by external reviewers) and the possibility of further cooperation with the institute depends on the resulting assessment. The current director of the Institute is prof. Assoc. Jacek Kuźnicki.
The Institute is one of the leading Polish research institutions. Thanks to the large number of publications in renown scientific journals worldwide it received the highest scientific category of A+. IIMCB also has a leading position among research institutions in the amount of the conducted projects as well as in the amount of funds raised for research per scientist (both Polish and foreign).
The Institute specializes in basic research in the field of molecular medicine. It deals with, among others, tumor biology, structural biology, neurobiology, bioinformatics, and enzymatic engineering. At the institute, the Center for Technology Transfer (Bio-Technology Innovations Platform) supports scientists in patenting and commercialization of technologies and inventions developed by them. As part of its operation it organizes networking meetings aimed at establishing contacts between scientists and entrepreneurs and conducts business trainings for employees.
The Institute is located on the Ochota Campus in Warsaw, in the immediate vicinity of many scientific and academic institutions, which are most active in the field of biology, medicine and bioengineering. Together with five institutes of Polish Academy of Science, it creates the Biocenter Ochota consortium aimed at strengthening cooperation in science and conducting major research projects.
Dr. Marcin Nowotny, Chief Scientific Officer
Dr. Marcin Nowotny, head of the Laboratory of Protein Structure at the International Institute of Molecular and Cell Biology in Warsaw, is a co-founder and the Principal Investigator of PRO Biostructures. He is a co-author of over 30 scientific publications (such as: Cell, Molecular Cell, EMBO Journal, Nature Structural Molecular Biology, Nature Communications). Dr. Nowotny has received prestigious research grants, such as EMBO Installation Grant, the ERC Starting Grant, the Wellcome Trust International Senior Research Fellowship (twice) and the Howard Hughes International Early Career Scientist Award. Between 2003 and 2008, he was a postdoctoral research fellow in the group of Wei Yang Laboratory, National Institutes of Health.
Pawel Kustosz, CEO
Pawel Kustosz is a co-founder and a manager of PRO Biostructures. He is a graduate of the University of Adam Mickiewicz in biotechnology as well as the Warsaw School of Economics in project management. He acquired his experience at the Mossakowski Medical Research Center of the Polish Academy of Sciences. There he also cooperated with the Central Clinical Hospital Ministry of Interior in Warsaw. During his work at the Laboratory of Protein Structure at the International Institute of Molecular and Cell Biology in Warsaw, he organized the IIMCB Structure Biology Center named PRO Biostructures.
Dr. Elzbieta Nowak, Chief Operating Officer
Dr. Elzbieta Nowak is an experienced crystallographer and a laboratory work coordinator in PRO Biostructures. She uses X-ray diffraction techniques to solve crystal structures of various proteins and nucleic acids of biological and medical relevance. She gained her experience at the highly acclaimed Advanced Photon Source at National Institutes of Health (NIH) in the US and at Deutsches Elektronen-Synchrotron (DESY) at The European Molecular Biology Laboratory (EMBL) in Hamburg. Currently she works in the Laboratory of Protein Structure at the International Institute of Molecular and Cell Biology in Warsaw.